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Acoziborole Rollout
The first single-dose oral cure begins deployment, enabling 'screen-and-treat' strategies.
Fexinidazole Approval
The first all-oral treatment is approved, requiring 10 days of pills taken with food.
NECT Launch
Nifurtimox-eflornithine combination therapy improves safety but requires complex intravenous administration.
Melarsoprol Introduced
Arsenic-based treatment becomes standard but carries a 5% mortality rate due to toxicity.
The introduction of acoziborole, the first single-dose oral treatment for Human African Trypanosomiasis (sleeping sickness), marks a pivotal shift in global health efforts. Developed through a non-profit partnership between DNDi and Sanofi, the drug offers a simplified path to disease elimination by 2030.