# Wave Life Sciences

Type: Company (WVE)

Source: Biotech Intelligence Brief — https://getbiobrief.com/entity/wave-life-sciences
Canonical HTML page: https://getbiobrief.com/entity/wave-life-sciences

## Recent coverage (2 stories)

### Wave's WVE-007 Silences Activin E by 88%, Sustained for 7.5 Months in Phase I
2026-08-04 04:01:27 · Sentiment: Neutral · Impact: 5/10 · Sources: 2

Wave Life Sciences presented Phase I data for WVE-007, an siRNA targeting Activin E, demonstrating up to 88% serum reduction sustained for over 7.5 months. The INLIGHT Phase IIa trial is now enrolling 160 patients across four cohorts, with a focus on BMI 35–50 and type 2 diabetes status, aiming to validate the RNA editing platform's potential for durable obesity treatment.
Full story: https://getbiobrief.com/story/wave-007-88-percent-activin-e-silencing

### Wave Life Sciences and Collegium FY2025 Results Signal RNA and Pain Pivot
2026-02-26 14:28:36 · Sentiment: Neutral · Impact: 5/10 · Sources: 2

Wave Life Sciences and Collegium Pharmaceutical reported full-year 2025 results, highlighting a transformative period for RNA editing and commercial pain management. Wave's clinical progress in AATD and DMD remains a primary valuation driver, while Collegium continues to optimize its specialized portfolio through strategic acquisitions.
Full story: https://getbiobrief.com/story/wave-life-sciences-collegium-fy2025-earnings-analysis

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