# William Sibold

Type: Person

Source: Biotech Intelligence Brief — https://getbiobrief.com/entity/william-sibold
Canonical HTML page: https://getbiobrief.com/entity/william-sibold

## Timeline

- **2025-12-31**: Patent Extension — Secured Rezdiffra patent protection through 2045.
- **2025-11-20**: DGAT-2 and siRNA Expansion — Acquired late-stage DGAT-2 inhibitor and six preclinical siRNA assets.
- **2025-09-15**: GLP-1 Acquisition — Madrigal paid $120 million upfront to acquire an oral GLP-1 program.
- **2025-03-01**: Rezdiffra Commercial Launch — First full year of Rezdiffra availability in the U.S. market for MASH.

## Recent coverage (1 stories)

### Madrigal’s Rezdiffra Surpasses $950M in 2025 as Pipeline Expands into GLP-1s
2026-02-24 00:14:25 · Sentiment: Positive · Impact: 7/10 · Sources: 5

Madrigal Pharmaceuticals reported a transformative 2025, with Rezdiffra net sales reaching $958.4 million during its first full year on the market. The company is aggressively pivoting toward a multi-asset metabolic powerhouse, integrating oral GLP-1 and DGAT-2 programs alongside its core MASH franchise.
Full story: https://getbiobrief.com/story/madrigal-pharma-q4-2025-earnings-rezdiffra-growth

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